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To examine relationships between nurses' work conditions and their health, work-related factors were first examined individually in relation to three indicators of health: self-reported general health, self-reported mental health, and absences from work for health-related reasons totalling at least 20 days in the past year. Work-related factors were organized into five groups. The first group pertained to tangible aspects of the job; its elements included usual shift worked, number of shift changes in past two weeks, having multiple jobs, hours worked per week, work setting and union coverage. The other four groups of work-related factors reflect a variety of interpersonal, social and psychological aspects of nurses' work, that are collectively referred to in this report as "psychosocial": work stress job strain, supervisor support, co-worker support, job insecurity, physical demands Nursing Work Index autonomy, control over practice, nursephysician working relations respect from superiors, from co-workers and role overload. Multivariate analysis see Analytical techniques ; was used to examine associations between work-related factors and health, while taking into account the potentially confounding effects of sex, age, type of nurse, province territory, household income, smoking and obesity control variables ; . Separate regression models were fitted for each of the three health indicators dependent variables ; . The multivariate analysis was designed to address the following questions: Are the tangible factors of work organization related to nurses' health? Do psychosocial factors of the job have an independent association with health, once the tangible factors are taken into account? The independent variables were entered into the models in five stages. Tangible work organization factors were entered in the first model, along with the control variables. Then each of the four groups of psychosocial factors work stress factors, Nursing Work Index, respect, and role overload ; was entered separately into four subsequent models, in which all of the tangible factors and control variables were retained. Thus, five models were produced for each of the three dependent variables general health, mental health, and high work absence for health-related reasons.
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Authors: B.S. Ang, R. Singh and Mohd Razip Samian * Address: Pusat Pengajian Sains Perubatan, USM 16150 Kubang Kerian, Kelantan * Pusat Pengajian Sains Kajihayat, USM, 11800 Minden, Pulau Pinang. Introduction: Maximal oxygen uptake VO2max ; is generally accepted as a valid method for measuring aerobic capacity which is expensive and impractical in many cases. However, there are also a number of field tests which are able to assess the cardiopulmonary fitness, and one such test is the 20m multi-shuttle run test 20MST ; which had been not validated on the Malaysian population. Objective: The purpose of this study was therefore to assess the correlation and validity of predicting VO2max of teenagers from the performance on the 20MST Methodology: Twenty two healthy male students age 17.7 0.2 yrs, height 168 1.2 cm and weight 62.6 1.4 kg ; participated in this study. The subjects did a continuous 20MST on a flat rough cement surface and a laboratory VO2max measurement on an incremental treadmill test TM ; . All tests were done randomly with at least 3 days between each test. Results: The average VO2max was 52.18 1.25 ml. kg-1. mim-1 with the average TM time of 10.88 0.46 min. The continuous 20MST give a total run score of 81.8 0.8 shuttles and with running time 9.88 0.30 min. The VO2max correlated significantly with 20MST run score r 0.80, p 0.0001 ; . The total running time for TM is significantly higher than 20MST p 0.0001 ; . Despite a significant lower running time, the 20MST time correlated significantly with TM time r 0.68, p 0.001 ; . The predicted VO2max 52.21 1.00 ml -1 n-1 ; derived from the correlation were not significant different from the actual measured VO2max. Conclusion: This study shown that test is a valid field test assess maximum aerobic capacity in Malaysian teenagers. It can also be used for exercise prescription in Malaysian teenagers.
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A PHYTOCHEMICAL INVESTIGATION OF THE GENUS MALLEASTRUM MELIACEAE FAMILY ; OF MADAGASCAR Vuyelwa J. Ndlebe1, 2, D. Mulholland1, P. Coombes2, H. Rabarison3, and M. Randrianarivelojosia 4 1 School of Biomedical and Molecular Sciences, University of Surrey, Guildford, GU2 7XH, U.K. 2 School of Chemistry, Howard College Campus, Univ. of Kwazulu-Natal, Durban, 4041, S. Africa 3 Facult des Sciences, Universit d'Antananarivo, Madagascar 4 Malaria Research Group, BP 1274, Antananarivo 101 ; , Institut Pasteur de Mad., Madagascar Natural Products Research Group Malleastrum Rakotozafyi and M. antsingyense are two of the twenty-four species of the genus Malleastrum Meliaceae ; 1. The plants of the Meliaceae are known to be used in traditional medicine to treat stomach pain, backache, fever and heart disease2. A phytochemical investigation of M. antsingyense and M. rakotozafyi has yielded two limonoids: 1, 3-diacetylvilasinin 1, three novel ent-isopimarane diterpenoids: ent-8-hydroxy isopimar-15-en-3-one 2, ent-3, 8-dihydroxy isopimar-15-ene, ent-8-hydroxy isopimar-15ene and two novel labdanes: ent-15, 16-epoxy labda-8 17 ; , 13 16 ; , 14-trien-3-ol 3, ent-15, 16epoxy labda-8 17 ; , 13 16 ; , 14-trien-3-one, and three known labdanes.The structures of the compounds were determined on the basis of their FTIR, MS, 1D, 2D NMR spectroscopic data and 17 15 O Optical rotation. 15, for instance, paxil drug.
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Obtain a unique interaction between the health sector, the salt producers and the commerce sector. Plans for future workshops and funding were discussed. Burkino Faso - A trial of iodized oil in two provinces is under evaluation, and a proposal for an IDD program has been prepared. Guinea Bissau - Three-fourths of the country has been surveyed, and goiter prevalence and urinary iodine levels assessed. A national program document needs to be prepared. Mali - A project for salt iodization in Bamako to cover one million persons has been prepared. The country needs a comprehensive national program. Water iodization is being pursued in Kita with the World Bank, and an iodized oil program is also in progress. An official IDD national committee has been created. Senegal - Salt iodization is described above. A national program draft also proposes iodized oil for a high risk population, and water iodization is being initiated as part of a combined program of water purification. Central African Republic - An analysis of salt commercialization shows a complex distribution pattern. Legislation and IEC are needed for the program. Rhone Poulenc is planning to install 500 water iodization units. The Congo has a regional program in progress. Rwanda needs approval for legislation of iodized salt and monitoring. Chad requires survey and further development of a program. Zaire has an iodized oil program still in progress. A major need is for laboratory support in Kinshasa. Dr. Kavishe, the Subregional Coordinator for East, Central, and Southern Africa ECSA ; , provided additional details for countries in that region. Botswana - A document for a national program has been drafted, with the main aims of elimination of IDD in affected areas, quality control of salt for local and external consumption, utilization of existing infrastructure for IDD control, and establishment of a formal intersectoral coordination mechanism. The major foci of the proposed program are IEC, and the quality control and monitoring of iodized salt. The proposal includes training for personnel. Ethiopia - The salt iodization program had been going well but was disrupted by civil strife in 1990. Iodized oil had also been given. The creation of Eritrea from Ethiopia alters the IDD program because all the iodization machinery and production sites are in Eritrea, where an organizational structure for IDD control still needs to be formed. Kenya - Salt iodization has been compulsory since 1989. Limited tests done so far on some samples reaching Tanzania have shown it to contain the required amount. Lesotho - IDD activities are integrated into the existing child nutrition program. Salt iodized at 20 ppm is imported from South Africa, and this level holds at the consumption level. IEC is a priority need. Malawi - IDD control activities are taking place but no formal national program exists. Iodized oil is the major control method. A policy to iodize salt on importation has been adopted and negotiations with several private companies are underway.
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Treatment Group: Paroxetine Adverse Experience: Depression This 12-year-old white male was a participant in the trial of BRL-29060 704, which was conducted in children and adolescents with obsessive-compulsive disorder OCD ; . The patient entered the study with a previous significant medical condition of sinusitis and a current medical condition of soft tissue disorder seashells in right foot, were not removed ; . Psychiatric history measured by K-SADS-PL interview ; includes previous major depressive disorder MDD ; and current OCD with an onset of January 1996, and current attention deficit disorder ADD ; with an onset of January 1993. Prior medications include Keflex cephalexin monohydrate ; as prophylaxis for an unknown condition. Concomitant medications include Pxil paroxetine ; for depression and OCD beginning 18 February 2000 and continuing post-study ; , and Ritalin methylphenidate HCl ; beginning 18 February 2000 and continuing post-study ; for depression and for attention deficit hyperactivity disorder ADHD ; . Post-treatment medications include Anaplex pseudoephedrine HCl ; for nasal congestion, and Adderall amphetamine aspartate, amphetamine sulfate, amphetamine saccharate ; for ADHD. The patient was randomized to the paroxetine regimen and received the first dose of study medication on 05 February 2000. The patient began treatment at a dose of 10 mg day and was titrated up to 20 mg day on 12 February 2000. On 17 February 2000, the patient experienced severe depression that resolved with treatment in 5 days. This non-serious event was considered by the investigator to be unrelated to treatment with study medication. The event resulted in withdrawal of the patient from the study. The patient discontinued study medication on 18 February 2000 Day 14 ; . No other non-serious adverse events were reported during the study. One nonserious adverse event was reported post-treatment. On 05 March 2000 Day 30 ; the patient reported mild rhinitis nasal congestion ; that resolved with treatment in.
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Nontraumatic limb loss 3 ; . This morbidity is compounded by the fact that of people with diabetes, 30% require amputation of the remaining limb at three years and 50% at four years after the first amputation 4 ; . The mortality rate of diabetic amputees is also increased, with a three-year survival rate of 50% 5 ; . Extremity complications in people with diabetes are complex in their etiology and management, and hence do not fall under the purview of one specific medical discipline. The objective of the present paper, therefore, was to design a concise.
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Anxiety disorder, and posttraumatic stress disorder. The conditions and duration of exposure to immediate-release paroxetine varied greatly and included in overlapping categories ; open and double-blind studies, uncontrolled and controlled studies, inpatient and outpatient studies, and fixed-dose and titration studies. Only those events not previously listed for controlled-release paroxetine are included. The extent to which these events may be associated with PAXIL CR is unknown. Events are listed alphabetically within the respective body system. Events of major clinical importance are also described in the PRECAUTIONS section. Body as a Whole: Infrequent were chills, face edema, fever, flu syndrome, malaise; rare were abscess, anaphylactoid reaction, anticholinergic syndrome, hypothermia; also observed were adrenergic syndrome, neck rigidity, sepsis. Cardiovascular System: Infrequent were angina pectoris, bradycardia, hematoma, hypertension, hypotension, palpitation, postural hypotension, supraventricular tachycardia, syncope; rare were bundle branch block; also observed were arrhythmia nodal, atrial fibrillation, cerebrovascular accident, congestive heart failure, low cardiac output, myocardial infarct, myocardial ischemia, pallor, phlebitis, pulmonary embolus, supraventricular extrasystoles, thrombophlebitis, thrombosis, vascular headache, ventricular extrasystoles. Digestive System: Infrequent were bruxism, dysphagia, eructation, gastritis, gastroenteritis, gastroesophageal reflux, gingivitis, hemorrhoids, liver function test abnormal, melena, pancreatitis, rectal hemorrhage, toothache, ulcerative stomatitis; rare were colitis, glossitis, gum hyperplasia, hepatosplenomegaly, increased salivation, intestinal obstruction, peptic ulcer, stomach ulcer, throat tightness; also observed were aphthous stomatitis, bloody diarrhea, bulimia, cardiospasm, cholelithiasis, duodenitis, enteritis, esophagitis, fecal impactions, fecal incontinence, gum hemorrhage, hematemesis, hepatitis, ileitis, ileus, jaundice, mouth ulceration, salivary gland enlargement, sialadenitis, stomatitis, tongue discoloration, tongue edema. Endocrine System: Infrequent were ovarian cyst, testes pain; rare were diabetes mellitus, hyperthyroidism; also observed were goiter, hypothyroidism, thyroiditis. Hemic and Lymphatic System: Infrequent were anemia, eosinophilia, hypochromic anemia, leukocytosis, leukopenia, lymphadenopathy, purpura; rare were thrombocytopenia; also observed were anisocytosis, basophilia, bleeding time increased, lymphedema, lymphocytosis, lymphopenia, microcytic anemia, monocytosis, normocytic anemia, thrombocythemia. Metabolic and Nutritional Disorders: Infrequent were generalized edema, hyperglycemia, hypokalemia, peripheral edema, SGOT increased, SGPT increased, thirst; rare were bilirubinemia, dehydration, hyperkalemia, obesity; also observed were alkaline phosphatase increased, BUN increased, creatinine phosphokinase increased, gamma globulins increased, gout, hypercalcemia, hypercholesteremia, hyperphosphatemia, hypocalcemia, hypoglycemia, hyponatremia, ketosis, lactic dehydrogenase increased, non-protein nitrogen NPN ; increased. Musculoskeletal System: Infrequent were arthritis, bursitis, tendonitis; rare were myasthenia, myopathy, myositis; also observed were generalized spasm, osteoporosis.
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